The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Jun. 24, 2021
Applicant:
Ksq Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Gregory V. Kryukov, Newton, MA (US);
Michael R. Schlabach, Belmont, MA (US);
Jason J. Merkin, Cambridge, MA (US);
Assignee:
KSQ Therapeutics, Inc., Lexington, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C40B 50/06 (2006.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01);
U.S. Cl.
CPC ...
C40B 50/06 (2013.01); C12N 15/1082 (2013.01); C12N 15/11 (2013.01); G16B 20/00 (2019.02); G16B 30/00 (2019.02); C12N 2310/20 (2017.05); C12N 2320/11 (2013.01); C12N 2330/50 (2013.01);
Abstract
The invention describes a novel system for identifying optimized gRNAs for use in CRISPR/Cas9 genome editing platforms. The invention allows for the determination of specific gene alterations rendered by a particular gRNA, thereby permitting the generation of optimized gRNA libraries.