The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Jul. 15, 2020
Applicant:

Samsung Life Public Welfare Foundation, Seoul, KR;

Inventors:

Duk Lyul Na, Seoul, KR;

Jong Wook Chang, Seoul, KR;

Hyo Jin Son, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0735 (2010.01); A61K 35/51 (2015.01); A61K 35/545 (2015.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); A61K 35/51 (2013.01); A61K 35/545 (2013.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); C12N 5/0665 (2013.01); C12N 2501/999 (2013.01);
Abstract

The present invention relates to a medium composition for reinforcing the efficacy of stem cells, including ethionamide, a method of reinforcing the efficacy of stem cells, including culturing stem cells in the medium composition, a method of preparing stem cells with reinforced efficacy, stem cells prepared by the above-mentioned method, and a use thereof. According to the present invention, the anti-inflammatory effect of mesenchymal stem cells and expression levels of paracrine factors may be effectively improved by a simple method of treating mesenchymal stem cells with ethionamide, and the stem cells obtained by the above method may be effectively used for preventing or treating an inflammatory disease or a degenerative brain disease.


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