The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Oct. 07, 2022
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Eric A. Appel, Palo Alto, CA (US);

Caitlin Maikawa, Boston, MA (US);

Joseph L. Mann, Mountain View, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08F 220/36 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
C08F 220/36 (2013.01); A61K 9/1272 (2013.01); A61K 9/5146 (2013.01);
Abstract

A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.


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