The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

May. 17, 2019
Applicant:

National Research Council of Canada, Ottawa, CA;

Inventors:

Marzia Martina, Ottawa, CA;

Balu Chakravarthy, Ottawa, CA;

Yves Durocher, Montreal, CA;

Mehdi Arbabi-Ghahroudi, Ottawa, CA;

Anne Marcil, Pierrefonds, CA;

Danica Stanimirovic, Ottawa, CA;

Traian Sulea, Kirkland, CA;

Maria Moreno, Ottawa, CA;

Umberto Banderali, Ottawa, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 29/00 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61P 29/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/22 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure concerns antibodies specific for the Na v.7 polypeptides which are capable of antagonizing the biological activity of the Na v.7 polypeptide. The anti-Na v.7 antibodies can be used for alleviating the symptoms of pain and/or for treating or alleviating the symptoms of an hyperproliferative disease. The presence disclosure also concerns immunogens and methods for making antibodies, such as the anti-Na v.7 antibodies, comprising a single-domain antibody.


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