The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Jun. 01, 2021
Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;
Vanderbilt University, Nashville, TN (US);
Jason Abbott, Libertyville, IL (US);
Joachim Broeker, Modling, AT;
Jianwen Cui, Franklin, TN (US);
Steve W. Fesik, Nashville, TN (US);
Andreas Gollner, Vienna, AT;
Tim Hodges, Chicago, IL (US);
Jale Karolyi-Oezguer, Vienna, AT;
Andrew Little, Sudbury, MA (US);
Andreas Mantoulidis, Vienna, AT;
Jason Phan, Nashville, TN (US);
Dhruba Sarkar, Karnataka, IN;
Christian Alan Paul Smethurst, Vienna, AT;
Qi Sun, Libertyville, IL (US);
Matthias Treu, Vienna, AT;
Alex Waterson, Murfreesboro, TN (US);
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Vanderbilt University, Nashville, TN (US);
Abstract
The present invention encompasses compounds of formula (I) wherein R, R, R, R, Z, Rto R, A, p, U, V, W, L and E have the meanings given in the claims and specification, their use as inhibitors of mutant Ras family proteins, pharmaceutical compositions and preparations containing such compounds and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.