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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11945799 B1

PDFFull Text
Date of Patent:
Apr. 02, 2024

Filed:

Mar. 28, 2023

4-ethynylpyridine derivatives useful as gcn2 inhibitors

Applicant:

Ip2ipo Innovations Limited, London, GB;

Inventors:

Gavin Whitlock, Deal, GB;

Matthew Fuchter, London, GB;

Assignee:

IP2IPO INNOVATIONS LIMITED, London, GB;

Attorney:

Haynes and Boone, LLP

Primary Examiner:

Savitha M Rao

Assistant Examiner:

Andrew P Lee

Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 45/06 (2013.01); C07D 401/06 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The invention provides compounds of formula I, wherein the substituents are as set out in further detail in the specification. The compounds are potent inhibitors of GCN2 and they have excellent pharmacokinetic properties. The compounds are useful for the treatment or prevention of a variety of conditions, particularly cancer. The invention further provides pharmaceutical compositions comprising the compounds of the invention and uses of the compounds and the compositions.

Find Patent Forward Citations

Whitlock, Gavin. (2024). 4-ethynylpyridine derivatives useful as gcn2 inhibitors (U.S. Patent No. 11945799). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11945799

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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