The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Sep. 17, 2020
Applicant:
Abraxis Bioscience, Llc, Summit, NJ (US);
Inventors:
Neil P. Desai, Pacific Palisades, CA (US);
Shihe Hou, Millington, NJ (US);
Assignee:
Abraxis BioScience, LLC, Summit, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 31/436 (2006.01); A61K 39/395 (2006.01); A61P 25/08 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 9/0019 (2013.01); A61K 31/436 (2013.01); A61K 39/3955 (2013.01); A61P 25/08 (2018.01);
Abstract
The present application provides methods of treating a CNS disorder (such as glioblastoma and epilepsy) in an individual, comprising systemically (e.g., intravenously or subcutaneously) administering to the individual an effective amount of a composition comprising nanoparticles comprising an mTOR inhibitor (such as a limus drug, such as sirolimus or a derivative thereof) and an albumin, optionally further comprising administering a second agent (such as an anti-VEGF antibody, a proteasome inhibitor, or an alkylating agent).