The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Aug. 09, 2017
Applicant:
Seagen Inc., Bothell, WA (US);
Inventor:
Philip Moquist, Seattle, WA (US);
Assignee:
Seagen Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/40 (2006.01); A61K 39/00 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); C07D 403/04 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6851 (2017.08); A61K 31/40 (2013.01); A61K 47/545 (2017.08); A61K 47/549 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08); A61K 47/6803 (2017.08); A61K 47/6867 (2017.08); A61K 47/6873 (2017.08); A61K 47/6889 (2017.08); A61P 35/00 (2018.01); C07D 403/04 (2013.01); C07K 16/2803 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract
Compounds and compositions are disclosed in which a Drug Unit is linked to a targeting Ligand Unit through a self-stabilizing Linker Unit from which a drug compound or active drug moiety is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed.