The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Aug. 24, 2021
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Brian R. Boettcher, Winchester, MA (US);
Shari Lynn Caplan, Lunenburg, MA (US);
Douglas S. Daniels, Arlington, MA (US);
Norio Hamamatsu, Belmont, MA (US);
Stuart Licht, Cambridge, MA (US);
Stephen Craig Weldon, Leominster, MA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/50 (2006.01); A61K 38/18 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); A61K 45/06 (2013.01); C07K 14/50 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.