The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Jun. 16, 2023
Applicant:

King Abdulaziz Univeristy, Jeddah, SA;

Inventors:

Sami-ullah Rather, Jeddah, SA;

Mohmmad Younus Wani, Jeddah, SA;

Hisham S. Bamufleh, Jeddah, SA;

Hesham Alhumade, Jeddah, SA;

Usman Saeed, Jeddah, SA;

Aqeel Ahmad Taimoor, Jeddah, SA;

Walid M. Alalayah, Jeddah, SA;

Irfan Ahmad Rather, Jeddah, SA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/7048 (2006.01); A61P 31/10 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 31/7048 (2013.01); A61P 31/10 (2018.01); C07D 471/04 (2013.01);
Abstract

Provided herein are ionic liquids that can be used as antifungal agents alone or in combination with Amphotericin B. Also disclosed are methods of synthesis of the ionic liquids and inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosure provides antifungal agents that potentiate the antifungal activity of Amphotericin B, a commonly used antifungal drug that could be used alone or in combination. This combination will help control and combat the infections caused by drug resistantin immunocompromised patients.


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