The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

Jul. 10, 2018
Applicant:

Gw Research Limited, Histon, GB;

Inventors:

Benjamin Whalley, Histon, GB;

William Hind, Histon, GB;

Royston Gray, Histon, GB;

Javier Fernandez-Ruiz, Histon, GB;

Eva De Lago, Madrid, ES;

Carmen Rodriguez-Cueto, Madrid, ES;

Laura Garcia-Toscano, Madrid, ES;

Irene Santos-Garcia, Madrid, ES;

Assignee:

GW Research Limited, Histon, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/353 (2006.01); A61K 31/00 (2006.01); A61K 31/05 (2006.01); A61K 31/192 (2006.01); A61K 31/575 (2006.01); A61K 36/185 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/658 (2023.05); A61K 31/192 (2013.01); A61K 31/353 (2013.01); A61K 31/575 (2013.01); A61K 36/185 (2013.01); A61P 25/28 (2018.01);
Abstract

The present invention relates to the use of cannabinoids in the treatment of a neurodegenerative disease or disorder. In particular the cannabinoids cannabidiolic acid (CBDA) and cannabidivarin (CBDV) were able to produce neuroprotective effects in a mouse model of neurodegenerative disease. In particular these effects were associated with the symptoms associated with amyotrophic lateral sclerosis (ALS). Furthermore, the combination of the cannabinoid tetrahydrocannabinol (THC) with the drug olexisome provided a synergistic disease modifying effect in a mouse model of neurodegenerative disease. In particular these effects were associated with the symptoms associated with ALS.


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