The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2024

Filed:

May. 08, 2023
Applicant:

Murray and Poole Enterprises Ltd, Gibraltar, GI;

Inventor:

Mark Nidorf, Menora, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); A61K 31/37 (2006.01); A61K 31/4365 (2006.01); A61K 31/616 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/165 (2013.01); A61K 31/37 (2013.01); A61K 31/4365 (2013.01); A61K 31/616 (2013.01); A61K 45/06 (2013.01);
Abstract

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.


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