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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11940757 B1

PDFFull Text
Date of Patent:
Mar. 26, 2024

Filed:

Jun. 22, 2021

Lens-free holographic optical system for high sensitivity label-free microbial growth detection and quantification for screening, identification, and susceptibility testing

Applicant:

Accelerate Diagnostics, Inc., Tucson, AZ (US);

Inventor:

Oleg Gusyatin, Tucson, AZ (US);

Assignee:

Accelerate Diagnostics, Inc., Tucson, AZ (US);

Attorney:

Wood Herron & Evans LLP

Primary Examiner:

Stephone B Allen

Assistant Examiner:

Tamara Y Washington

Int. Cl.
CPC ...
G03H 1/10 (2006.01); C12M 1/34 (2006.01); G01N 15/02 (2006.01); G01N 15/0227 (2024.01); G01N 15/10 (2006.01); G01N 15/14 (2006.01); G01N 15/1434 (2024.01); G01N 23/20 (2018.01); G02B 21/00 (2006.01); G02B 21/36 (2006.01); G03H 1/00 (2006.01); G03H 1/04 (2006.01); G03H 1/08 (2006.01); G03H 1/26 (2006.01);
U.S. Cl.
CPC ...
G03H 1/10 (2013.01); C12M 41/36 (2013.01); G01N 15/0227 (2013.01); G01N 15/1434 (2013.01); G01N 15/1475 (2013.01); G01N 23/20 (2013.01); G02B 21/0008 (2013.01); G02B 21/365 (2013.01); G03H 1/0443 (2013.01); G01N 2015/0233 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1454 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01); G03H 2001/0033 (2013.01); G03H 2001/0447 (2013.01); G03H 1/0866 (2013.01); G03H 2001/2655 (2013.01); G03H 2222/13 (2013.01); G03H 2222/52 (2013.01); G03H 2226/13 (2013.01); G03H 2227/03 (2013.01);
Abstract

Disclosed are optical interrogation apparatus that can produce lens-free images using an optoelectronic sensor array to generate a holographic image of sample objects, such as microorganisms in a sample. Also disclosed are methods of detecting and/or identifying microorganisms in a biological sample, such as microorganisms present in low levels. Also disclosed are methods of using systems to detect microorganisms in a biological sample, such as microorganisms present in low levels. In addition or as an alternative, the methods of using systems may identify microorganisms present in a sample and/or determine antimicrobial susceptibility of such microorganisms.

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