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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11939609 B1

PDFFull Text
Date of Patent:
Mar. 26, 2024

Filed:

May. 01, 2019

Rewiring aberrant cancer signaling to a therapeutic effector response with a synthetic two-component system

Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Hokyung Chung, Mountain View, CA (US);

Michael Z. Lin, Stanford, CA (US);

Assignee:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Attorneys:

Jenny L. Buchbinder

Bozicevic, Field & Francis LLP

Primary Examiner:

Ileana Popa

Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/535 (2006.01); C12N 9/22 (2006.01); C12N 9/50 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 9/506 (2013.01); A61P 35/00 (2018.01); C07K 14/4702 (2013.01); C07K 14/4747 (2013.01); C07K 14/535 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12Y 304/21098 (2013.01); A61K 38/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/50 (2013.01); C07K 2319/70 (2013.01); C12N 15/1136 (2013.01); C12N 2310/20 (2017.05); C12N 2740/15033 (2013.01); C12N 2740/15043 (2013.01); C12N 2800/80 (2013.01);
Abstract

Compositions and methods for targeted treatment of cancer are disclosed. In particular, the invention relates to methods of targeting anti-cancer therapy to cells exhibiting aberrant signaling associated with cancer pathogenesis by administering synthetic signaling proteins that couple detection of an oncogenic signal to release of therapeutic agents into cancerous cells.

Find Patent Forward Citations

Chung, Hokyung. (2024). Rewiring aberrant cancer signaling to a therapeutic effector response with a synthetic two-component system (U.S. Patent No. 11939609). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11939609

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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