The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
May. 01, 2019
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Hokyung Chung, Mountain View, CA (US);
Michael Z. Lin, Stanford, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/535 (2006.01); C12N 9/22 (2006.01); C12N 9/50 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 9/506 (2013.01); A61P 35/00 (2018.01); C07K 14/4702 (2013.01); C07K 14/4747 (2013.01); C07K 14/535 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12Y 304/21098 (2013.01); A61K 38/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/50 (2013.01); C07K 2319/70 (2013.01); C12N 15/1136 (2013.01); C12N 2310/20 (2017.05); C12N 2740/15033 (2013.01); C12N 2740/15043 (2013.01); C12N 2800/80 (2013.01);
Abstract
Compositions and methods for targeted treatment of cancer are disclosed. In particular, the invention relates to methods of targeting anti-cancer therapy to cells exhibiting aberrant signaling associated with cancer pathogenesis by administering synthetic signaling proteins that couple detection of an oncogenic signal to release of therapeutic agents into cancerous cells.