The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

Mar. 14, 2018
Applicant:

Seattle Children's Hospital, Seattle, WA (US);

Inventors:

David J. Rawlings, Seattle, WA (US);

Richard James, Seattle, WA (US);

Shaun W. Jackson, Seattle, WA (US);

Iram Khan, Issaquah, WA (US);

King Hung, Seattle, WA (US);

Andrew M. Scharenberg, Seattle, WA (US);

Assignee:

Seattle Children's Hospital, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); A61K 48/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C12N 5/00 (2006.01); C12N 5/078 (2010.01); C12N 5/0781 (2010.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01); A61K 35/17 (2015.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0634 (2013.01); A61K 48/0058 (2013.01); C07K 14/00 (2013.01); C07K 16/00 (2013.01); C12N 5/0635 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/90 (2013.01); A61K 35/17 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C12N 15/113 (2013.01); C12N 2310/20 (2017.05); C12N 2501/056 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/231 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/24 (2013.01); C12N 2501/52 (2013.01); C12N 2506/11 (2013.01); C12N 2510/00 (2013.01); C12N 2510/02 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/80 (2013.01);
Abstract

The present application relates to plasma cells and plasma cell precursors that express a macromolecule, such as a protein, protein mimetic or a peptide and compositions comprising these plasma cells or plasma cell precursors. The application further relates to methods of using and making the plasma cells and plasma cell precursors that express the macromolecule. Methods of treatment comprising administering the plasma cells or plasma cell precursors are also contemplated.


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