The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Jul. 25, 2018
Applicant:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
Katherine A. High, Merion Station, PA (US);
Federico Mingozzi, Philadelphia, PA (US);
Junwei Sun, Philadelphia, PA (US);
Philip Johnson, Wynnewood, PA (US);
Assignee:
THE CHILDEN'S HOSPITAL OF PHILADELPHIA, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 38/36 (2006.01); C12N 15/12 (2006.01); C12N 15/86 (2006.01); C12N 15/864 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 targets polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.