The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

May. 29, 2019
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Michael Didonato, San Diego, CA (US);

Christoph Erkel, Puchheim, DE;

Anna Galkin, Encinitas, CA (US);

Scott Glaser, San Diego, CA (US);

Klaus Felix Hartlepp, Munich, DE;

Yong Jia, San Diego, CA (US);

Alexandra Kraus, Munich, DE;

Christian Cho-Hua Lee, San Diego, CA (US);

Sarah Michelle Rue, San Diego, CA (US);

Jian Shi, San Diego, CA (US);

Xenia Karola Wezler, Munich, DE;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/39541 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided herein are antibodies or antigen-binding fragments thereof, e.g., monoclonal antibodies or antigen binding fragments thereof, that specifically bind to ENTPD2 (e.g., human ENTPD2 protein), and methods of using these antibodies or antigen-binding fragments. The present invention also relates to combination therapies comprising an anti-human ENTPD2 antibody or antigen binding fragment and at least one additional therapeutic agent, and methods of using these combination therapies.


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