The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Oct. 21, 2016
Merus N.v., Utrecht, NL;
Fundació Institut DE Recerca Biomèdica (Irb Barcelona), Barcelona, ES;
Institució Catalana DE Recerca I Estudis Avançats, Barcelona, ES;
Mark Throsby, Utrecht, NL;
Ton Logtenberg, Utrecht, NL;
Johannes Carolus Clevers, Utrecht, NL;
Robert Gerhardus Jacob Vries, Utrecht, NL;
Eduard Batlle, Barcelona, ES;
Bram Herpers, Leiden, NL;
Merus N.V., Utrecht, NL;
Fundacio Institut de Recerca Biomedica, Barcelona, ES;
Institució Catalana de Recerca I Estudis Avancats, Barcelona, ES;
Abstract
The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.