The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

Aug. 28, 2020
Applicant:

Five Prime Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Charles Kaplan, South San Francisco, CA (US);

Alessandro Palumbo, South San Francisco, CA (US);

Kathy Miller, South San Francisco, CA (US);

Hangil Park, South San Francisco, CA (US);

Nerissa Mendoza, South San Francisco, CA (US);

Majid Ghoddusi, South San Francisco, CA (US);

Assignee:

FIVE PRIME THERAPEUTICS, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); G01N 33/57492 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); G01N 2333/70532 (2013.01);
Abstract

The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.


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