The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Mar. 01, 2021
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Pfizer Inc., New York, NY (US);
Carl F. Ware, Solana Beach, CA (US);
John Sedy, San Diego, CA (US);
Tigran Aivazian, San Diego, CA (US);
Brian Miller, San Diego, CA (US);
Natasha K. Crellin, San Carlos, CA (US);
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Pfizer Inc., New York, NY (US);
Abstract
The present invention is based on the seminal discovery that BTLA agonist fusion proteins modulate an immune response. Specifically, the present invention provides fusion proteins that bind BTLA enhancing BTLA signaling. The present invention further provides methods of treating cancer and immune and inflammatory diseases and disorders with a BTLA agonist fusion protein as described herein.