The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

Mar. 15, 2021
Applicant:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Peter Kwong, Washington, DC (US);

Ivelin Georgiev, Nashville, TN (US);

Michael Gordon Joyce, Washington, DC (US);

Masaru Kanekiyo, Chevy Chase, MD (US);

Aliaksandr Druz, Germantown, MD (US);

Ulrich Baxa, Frederick, MD (US);

Joseph Van Galen, North Wales, PA (US);

Cheng Cheng, Rockville, MD (US);

John Mascola, Rockville, MD (US);

Yaroslav Tsybovsky, Brunswick, MD (US);

Yongping Yang, Potomac, MD (US);

Barney Graham, Rockville, MD (US);

Syed Mohammad Moin, Bethesda, MD (US);

Jeffrey Boyington, Clarksburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/11 (2006.01); A61K 39/21 (2006.01); C07K 14/08 (2006.01); C07K 14/16 (2006.01); C07K 14/165 (2006.01); C07K 14/435 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/11 (2013.01); A61K 39/21 (2013.01); C07K 14/082 (2013.01); C07K 14/162 (2013.01); C07K 14/165 (2013.01); C07K 14/43563 (2013.01); C12N 7/00 (2013.01); A61K 2039/55555 (2013.01); C07K 2319/735 (2013.01); C12N 2740/16134 (2013.01); C12N 2760/16134 (2013.01); C12N 2770/20034 (2013.01);
Abstract

Disclosed are recombinant insect ferritin nanoparticles that can be used to display two different trimeric antigens at an equal ratio. Also disclosed are nucleic acids encoding the recombinant insect ferritin nanoparticles and methods of producing the recombinant insect ferritin nanoparticles. Methods for eliciting an immune response in a subject are also provided.


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