The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Mar. 23, 2021
Applicants:
Howard Hughes Medical Institute, Chevy Chase, MD (US);
The Regents of the University of California, Oakland, CA (US);
Inventors:
Joshua Dudman, Leesburg, VA (US);
Adam Hantman, Ashburn, VA (US);
Bum-Yeol Hwang, Moraga, CA (US);
Alla Karpova, Ashburn, VA (US);
Loren Looger, Sterling, VA (US);
Kimberly Ritola, Ashburn, VA (US);
David Schaffer, Danville, CA (US);
Dougal Gowanlock Robinson Tervo, Ashburn, VA (US);
Sarada Viswanathan, Ashburn, VA (US);
Assignee:
Howard Hughes Medical Institute, Chevy Chase, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C07K 14/005 (2006.01); C07K 14/015 (2006.01); C12N 15/86 (2006.01); C40B 30/06 (2006.01); C40B 40/08 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/015 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C40B 30/06 (2013.01); C40B 40/08 (2013.01); A61K 48/00 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14145 (2013.01); C12N 2810/6027 (2013.01);
Abstract
The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.