The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Mar. 25, 2020
Applicant:
Procos S.p.a., Cameri, IT;
Inventors:
Alberto Lena, Cameri, IT;
Antonio Toppino, Cameri, IT;
Katia Miele, Settala, IT;
Jacopo Roletto, Cameri, IT;
Paolo Paissoni, Cameri, IT;
Assignee:
PROCOS S.P.A., Cameri, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/22 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01);
Abstract
A process for the preparation of midostaurin with high purity, particularly a process for the preparation of midostaurin with a content of oxidation impurities lower than 0.1% comprising the treatment of crude midostaurin or staurosporine with strong organic or inorganic acids in a water-immiscible solvent and, optionally, also with reducing silanes is described.