The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

Aug. 20, 2018
Applicant:

Politechnika Gdanska, Gdansk, PL;

Inventors:

Sebastian Demkowicz, Gdansk, PL;

Mateusz Dasko, Pruszcz Gdanski, PL;

Janusz Rachon, Gdansk, PL;

Assignee:

Politechnika Gdanska, Gdansk, PL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/06 (2006.01); A61P 35/00 (2006.01); G01N 33/573 (2006.01); A61K 31/4192 (2006.01);
U.S. Cl.
CPC ...
C07D 249/06 (2013.01); A61P 35/00 (2018.01); G01N 33/573 (2013.01); A61K 31/4192 (2013.01);
Abstract

The present invention relates to 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives and derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol as new compounds. The subject of the invention is the medical use of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives and the medical use of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol derivatives. The subject of the invention is the use of new compounds as an agent with the properties of a steroid sulfatase inhibitor and/or an estrogen receptor modulator. The present invention relates to the medical use of novel compounds for use as an antimicrobial medicament and/or estrogen receptor modulator. In particular, 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives are for use as medicament in cancer therapy. The invention also relates to a process for the preparation of these new compounds, wherein the derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol are the intermediate product from which the sulfamate derivatives are obtained.


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