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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11938188 B1

PDFFull Text
Date of Patent:
Mar. 26, 2024

Filed:

Mar. 01, 2021

Injectable slurries and methods of manufacturing and using the same

Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Lilit Garibyan, Newton, MA (US);

Richard Rox Anderson, Boston, MA (US);

William A. Farinelli, Boston, MA (US);

Emilia Javorsky, Watertown, MA (US);

Assignee:

The General Hospital Corporation, Boston, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Andrew S Rosenthal

Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/045 (2006.01); A61K 31/047 (2006.01); A61K 31/137 (2006.01); A61K 31/167 (2006.01); A61K 31/245 (2006.01); A61K 31/445 (2006.01); A61K 31/7004 (2006.01); A61K 31/718 (2006.01); A61K 31/765 (2006.01); A61K 33/00 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01); A61K 47/28 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61K 31/045 (2013.01); A61K 31/047 (2013.01); A61K 31/137 (2013.01); A61K 31/167 (2013.01); A61K 31/245 (2013.01); A61K 31/445 (2013.01); A61K 31/7004 (2013.01); A61K 31/718 (2013.01); A61K 31/765 (2013.01); A61K 33/00 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/18 (2013.01); A61K 47/26 (2013.01); A61K 47/28 (2013.01);
Abstract

One aspect of the invention provides a slurry comprising: a plurality of sterile ice particles having a largest cross-sectional dimension less than about 1.5 mm; and a biocompatible surfactant. Another aspect of the invention provides a slurry including: a plurality of sterile ice particles having a largest cross-sectional dimension less than about 1.5 mm; a biocompatible surfactant; and a foam comprising a plurality of gas bubbles. Another aspect of the invention provides a slurry including: a plurality of sterile ice particles having a largest cross-sectional dimension less than about 1.5 mm; and a biocompatible excipient. Another aspect of the invention provides a slurry including: a plurality of sterile ice particles having a largest cross-sectional dimension less than about 1.5 mm; and a lipolytic agent.

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