The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2024

Filed:

Dec. 19, 2022
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Ching-Shih Chen, Columbus, OH (US);

Christopher C. Coss, Columbus, OH (US);

Samuel Kulp, Columbus, OH (US);

Yu-Chou Tseng, Columbus, OH (US);

Tanios Bekaii-Saab, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 45/06 (2006.01); A61P 21/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/167 (2013.01); A61K 45/06 (2013.01); A61P 21/06 (2018.01);
Abstract

In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.


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