The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2024
Filed:
Mar. 16, 2021
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventors:
Andrew D. Badley, Rochester, MN (US);
Amy M. Nguyen, Salt Lake City, UT (US);
Scott H. Kaufmann, Rochester, MN (US);
Yuan-Ping Pang, Rochester, MN (US);
Haiming Dai, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 31/635 (2006.01); A61P 31/18 (2006.01); A61K 31/21 (2006.01); A61K 38/20 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/00 (2013.01); A61K 31/635 (2013.01); A61P 31/18 (2018.01); A61K 31/21 (2013.01); A61K 38/2013 (2013.01); A61K 45/06 (2013.01);
Abstract
This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or more Bcl-2 inhibitors (e.g., ABT-199) alone or in combination with one or more agents capable of reactivating HIV (e.g., latency reversing agent) to kill HIV infected cells (e.g., CD4 T cells) are provided.