The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2024

Filed:

Aug. 17, 2022
Applicant:

Functional Fluidics Inc., Detroit, MI (US);

Inventors:

Michael Tarasev, Pinckney, MI (US);

Xiufeng Gao, Windsor, CA;

Marta Ferranti, Chesterfield, MI (US);

Assignee:

Functional Fluidics Inc., Detroit, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/49 (2006.01); C07K 14/805 (2006.01); C12N 5/078 (2010.01); C12N 9/02 (2006.01); C12Q 1/26 (2006.01); G01N 33/50 (2006.01); G01N 33/72 (2006.01); G01N 33/80 (2006.01);
U.S. Cl.
CPC ...
G01N 33/4925 (2013.01); C07K 14/805 (2013.01); C12N 5/0641 (2013.01); C12N 9/0069 (2013.01); C12Q 1/26 (2013.01); G01N 33/5026 (2013.01); G01N 33/721 (2013.01); G01N 33/80 (2013.01); G01N 2333/90241 (2013.01);
Abstract

A method for assessing an effect, such as a treatment, disease, or passage of time on a cellular unit of an organism includes providing a sample including a cellular unit subject to the effect in a supporting medium in a hermetically sealed container. The container is deoxygenated to induce at least one of a predetermined amount of hypoxia and a predetermined rate of oxygen consumption in the medium. Values for variables associated with the medium and/or the cellular unit are determined at each of a plurality of different times. Various combinations of the predetermined amount of hypoxia, the predetermined rate of oxygen consumption, the values for the variables associated with the medium and/or cellular unit, and the times and then correlated to generate a multi-dimensional surface. This surface is compared with another surface correlating corresponding values relating to another cellular unit such as one not subject to the effect.


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