The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
Apr. 19, 2017
Kapa Biosystems, Inc., Wilmington, MA (US);
Martin Ranik, Cape Town, ZA;
Eric Van der Walt, Western Cape, ZA;
William Bourn, Western Cape, ZA;
Jennifer Hsieh, Cape Town, ZA;
Abre De Beer, Zevenwacht Country Estate, ZA;
Gerrida Uys, Cape Town, ZA;
Paul McEwan, Camps Bay, ZA;
KAPA BIOSYSTEMS, INC., Wilmington, MA (US);
Abstract
Disclosed is a method of fragmenting DNA comprising contacting a sample of target DNA with (a) a composition comprising an active transpososome, and (b) a composition comprising an inactive transpososome, under conditions suitable for transpososome activity, wherein a ratio of an amount of the inactive transpososome in the composition of (b) to an amount of the active transpososome in the composition of (a) determines the mean fragment size and a level of insertion bias.