The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
Oct. 09, 2020
Genentech, Inc., South San Francisco, CA (US);
Xencor, Inc., Pasadena, CA (US);
John Desjarlais, Pasadena, CA (US);
Matthew Bernett, Pasadena, CA (US);
Michael Hedvat, Pasadena, CA (US);
Rajat Varma, Pasadena, CA (US);
Suzanne Schubbert, Pasadena, CA (US);
Christine Bonzon, Pasadena, CA (US);
Rumana Rashid, Pasadena, CA (US);
Juan Diaz, Pasadena, CA (US);
Patrick Holder, South San Francisco, CA (US);
Christine Huang, South San Francisco, CA (US);
GENENTECH, INC., South San Francisco, CA (US);
XENCOR, INC., Pasadena, CA (US);
Abstract
The present invention relates to fusion proteins comprising variant IL-15 proteins, fusion proteins comprising variant anti-PD-1 antigen binding domains, and fusion proteins comprising variant IL-15 proteins and variant anti-PD-1 antigen binding domains. The present invention also relates to nucleic acid molecules, expression vectors, host cells and methods for making such fusion proteins and the use of such fusion proteins in the treatment of cancer.