The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
Jul. 11, 2018
Maxion Therapeutics Limited, Cambridge, GB;
Aneesh Karatt Vellatt, Sawston Cambridgeshire, GB;
John McCafferty, Sawston Cambridgeshire, GB;
Sachin Badrinath Surade, Sawston Cambridgeshire, GB;
Tim Luetkens, Salt Lake City, UT (US);
Edward William Masters, Sawston Cambridgeshire, GB;
Michael Richard Dyson, Sawston Cambridgeshire, GB;
Damian Colin Bell, Sawston Cambridgeshire, GB;
MAXION THERAPEUTICS LIMITED, Sawston Cambs, GB;
Abstract
Binding members for sodium channel Nav1.7 and their use in medicine including for treatment of pain or epilepsy. Binding members comprise a fusion protein containing a Nav1.7-binding peptide, e.g., venom toxin peptide or knottin ('donor diversity scaffold domain') inserted within an antibody variable domain (“recipient diversity scaffold domain”), and a partner domain (e.g., antibody variable domain), optionally wherein the partner domain enhances specificity of binding to Nav1.7 over other sodium channels.