The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2024

Filed:

May. 11, 2018
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Tufts Medical Center, Inc., Boston, MA (US);

Inventors:

Mohammad Movassaghi, Lincoln, MA (US);

Alyssa H. Antropow, Boston, MA (US);

Rachel J. Buchsbaum, Winchester, MA (US);

Kun Xu, Dorchester, MA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); A61P 35/04 (2006.01); C07D 498/22 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); A61P 35/04 (2018.01); C07D 498/22 (2013.01);
Abstract

The present disclosure relates to derivatized agelastatin compounds and methods for the treatment, prevention, or delay of cancer, comprising administering a therapeutically effect amount of the derivatized agelastatin compounds, a pharmaceutically acceptable salt thereof, or a composition thereof to a subject in need thereof. Methods for making the derivatized agelastatin compounds are also provided.


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