IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11932601 B1

PDFFull Text
Date of Patent:
Mar. 19, 2024

Filed:

Dec. 16, 2021

Immunoregulatory agents

Applicant:

Flexus Biosciences, Inc., Princeton, NJ (US);

Inventors:

Hilary Plake Beck, Emerald Hills, CA (US);

Juan Carlos Jaen, Burlingame, CA (US);

Maksim Osipov, Belmont, CA (US);

Jay Patrick Powers, Pacifica, CA (US);

Maureen Kay Reilly, Belmont, CA (US);

Hunter Paul Shunatona, San Francisco, CA (US);

James Ross Walker, Menlo Park, CA (US);

Mikhail Zibinsky, Lodi, CA (US);

James Aaron Balog, Lambertville, NJ (US);

David K. Williams, Delran, NJ (US);

Weiwei Guo, Lawrenceville, NJ (US);

Assignee:

Flexus Biosciences, Inc., Princeton, NJ (US);

Attorney:

BakerHostetler

Primary Examiner:

Karl J Puttlitz

Int. Cl.
CPC ...
C07D 213/75 (2006.01); A61K 31/167 (2006.01); A61K 31/195 (2006.01); A61K 31/277 (2006.01); A61K 31/343 (2006.01); A61K 31/426 (2006.01); A61K 31/44 (2006.01); A61K 31/505 (2006.01); A61K 31/5375 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); C07C 233/11 (2006.01); C07C 233/15 (2006.01); C07C 233/28 (2006.01); C07C 233/29 (2006.01); C07C 233/66 (2006.01); C07C 235/26 (2006.01); C07C 235/36 (2006.01); C07C 235/38 (2006.01); C07C 237/20 (2006.01); C07C 237/22 (2006.01); C07C 255/57 (2006.01); C07C 255/60 (2006.01); C07C 317/40 (2006.01); C07C 317/44 (2006.01); C07C 321/28 (2006.01); C07C 323/41 (2006.01); C07D 207/27 (2006.01); C07D 213/56 (2006.01); C07D 231/12 (2006.01); C07D 239/42 (2006.01); C07D 277/30 (2006.01); C07D 295/15 (2006.01); C07D 295/155 (2006.01); C07D 309/04 (2006.01); C07D 309/06 (2006.01); C07D 317/46 (2006.01); C07D 317/66 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); A61K 31/167 (2013.01); A61K 31/195 (2013.01); A61K 31/277 (2013.01); A61K 31/343 (2013.01); A61K 31/426 (2013.01); A61K 31/44 (2013.01); A61K 31/505 (2013.01); A61K 31/5375 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01); C07C 233/11 (2013.01); C07C 233/15 (2013.01); C07C 233/28 (2013.01); C07C 233/29 (2013.01); C07C 233/66 (2013.01); C07C 235/26 (2013.01); C07C 235/36 (2013.01); C07C 235/38 (2013.01); C07C 237/20 (2013.01); C07C 237/22 (2013.01); C07C 255/57 (2013.01); C07C 255/60 (2013.01); C07C 317/40 (2013.01); C07C 317/44 (2013.01); C07C 321/28 (2013.01); C07C 323/41 (2013.01); C07D 207/27 (2013.01); C07D 213/56 (2013.01); C07D 231/12 (2013.01); C07D 239/42 (2013.01); C07D 277/30 (2013.01); C07D 295/15 (2013.01); C07D 295/155 (2013.01); C07D 309/04 (2013.01); C07D 309/06 (2013.01); C07D 317/46 (2013.01); C07D 317/66 (2013.01); A61K 2039/55511 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); Y02A 50/30 (2018.01);
Abstract

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

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