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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11931465 B1

PDFFull Text
Date of Patent:
Mar. 19, 2024

Filed:

Mar. 08, 2017

Functionalized prussian blue nanoparticles, combination prussian blue nanoparticle-based nano-immunotherapy and applications thereof

Applicant:

Children's National Medical Center, Washington, DC (US);

Inventors:

Rohan Fernandes, Washington, DC (US);

Raymond W. Sze, Washington, DC (US);

Conrad Russell Y. Cruz, Washington, DC (US);

Anthony D. Sandler, Washington, DC (US);

Catherine M. Bollard, Washington, DC (US);

Elizabeth E. Sweeney, Washington, DC (US);

Juliana Cano-Mejia, Washington, DC (US);

Rachel Burga, Washington, DC (US);

Matthieu F. Dumont, Washington, DC (US);

Assignee:

Children's National Medical Center, Washington, DC (US);

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Melissa J Perreira

Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); A61K 9/127 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 33/26 (2006.01); A61K 35/17 (2015.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01); A61K 39/395 (2006.01); A61K 41/00 (2020.01); A61K 45/06 (2006.01); A61K 47/69 (2017.01); A61N 5/06 (2006.01); A61P 35/00 (2006.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5146 (2013.01); A61K 9/127 (2013.01); A61K 9/5068 (2013.01); A61K 9/5169 (2013.01); A61K 33/26 (2013.01); A61K 35/17 (2013.01); A61K 38/193 (2013.01); A61K 38/195 (2013.01); A61K 38/20 (2013.01); A61K 38/21 (2013.01); A61K 39/39541 (2013.01); A61K 41/0052 (2013.01); A61K 45/06 (2013.01); A61K 47/6901 (2017.08); A61K 47/6935 (2017.08); A61N 5/0616 (2013.01); A61N 5/062 (2013.01); A61N 5/0624 (2013.01); A61N 5/0625 (2013.01); A61P 35/00 (2018.01); A61N 5/0601 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0663 (2013.01); A61N 5/067 (2021.08);
Abstract

Combination treatment with Prussian blue nanoparticles and at least one immunotherapeutic treatment. Stable, functionalized Prussian blue nanoparticles, including those with enhanced stability under alkaline conditions, and methods of cancer, neoplasm, and tumor treatment using them, including photothermal treatment and combination immunotherapeutic treatments.

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