The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2024

Filed:

Nov. 18, 2021
Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Kaushal Rege, Chandler, AZ (US);

Rajeshwar Nitiyanandan, Tempe, AZ (US);

Tanya Nanda, Tempe, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); A61K 9/127 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/1273 (2013.01); A61K 35/12 (2013.01); A61K 47/6903 (2017.08);
Abstract

The instant disclosure is directed to compositions comprising an encapsulated spheroid, and methods of making and using the same. A composition may comprise a spheroid comprising a plurality of cells and aminoglycoside antibiotic-derived hydrogel beads, wherein the spheroid is encapsulated by the aminoglycoside antibiotic-derived hydrogel beads to form an encapsulated spheroid. A method may comprise administering the composition to a subject in need thereof. Another method may comprise administering a compound to the encapsulated spheroid. A method of creating an encapsulated spheroid may comprise coating a surface with an aminoglycoside antibiotic-derived hydrogel, culturing a plurality of cells on the surface, thereby creating a spheroid, and encapsulating the spheroid with a plurality of aminoglycoside antibiotic-derived hydrogel beads.


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