The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
Mar. 07, 2018
Psomagen, Inc., Rockville, MD (US);
Zachary Apte, San Francisco, CA (US);
Jessica Richman, San Francisco, CA (US);
Daniel Almonacid, San Francisco, CA (US);
Melissa Alegria, San Francisco, CA (US);
Valeria Marquez, San Francisco, CA (US);
Eduardo Morales, San Francisco, CA (US);
Rodrigo Ortiz, San Francisco, CA (US);
Janet Torres, San Francisco, CA (US);
Paulo Covarrubias, San Francisco, CA (US);
Javier Gimpel, San Francisco, CA (US);
Ingrid Araya, San Francisco, CA (US);
PSOMAGEN, INC., Rockville, MD (US);
Abstract
Therapeutic compositions and an associated method for improving a Toll-like receptor (TLR)-related condition, including determining a set of peptide sequences associated with a microorganism-related modulator of a TLR, determining a first set of binding parameters for the set of peptide sequences in relation to the TLR, selecting a target subset of peptide sequences from the set of peptide sequences based on the first set of binding parameters, reengineering the target subset of peptide sequences based on mutating amino acid residues of the target subset of peptide sequences, determining a second set of binding parameters for the reengineered target subset of peptide sequences in relation to the TLR, and identifying a first peptide for use in a therapeutic composition for improving the TLR-related condition, based on the second set of binding parameters for the reengineered target subset of peptide sequences.