The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
May. 14, 2021
Applicant:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Inventor:
Raymond J. Bergeron, Jr., Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); C07D 277/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); C07D 277/10 (2013.01);
Abstract
Macular degeneration, closed head injury, stroke, irritable bowel disease, and reperfusion injury are all associated with biological injury due to reactive oxygen species, probably due to focal iron overload in many instances. The present invention provides methods and pharmaceutical compositions for treating these diseases and conditions using desferrithiocin analogs of Formula (I). In certain embodiments, the analogs include a poly ether moiety at the 4′-position of the phenyl ring of the compound.