The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2024

Filed:

May. 19, 2021
Applicant:

Amazentis SA, Lausanne, CH;

Inventors:

Christopher L. Rinsch, Lausanne, CH;

William Blanco-Bose, La Croix, CH;

Bernard Schneider, Pully, CH;

Laurent Mouchiroud, Morges, CH;

Dongryeol Ryu, Renens, CH;

Penelope Andreux, Eclepens, CH;

Johan Auwerx, Buchillon, CH;

Assignee:

Amazentis SA, Lausanne, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/37 (2006.01); A61K 31/00 (2006.01); A61K 31/366 (2006.01); A61K 31/7048 (2006.01); A61K 45/06 (2006.01); C07D 311/80 (2006.01);
U.S. Cl.
CPC ...
A61K 31/37 (2013.01); A61K 31/00 (2013.01); A61K 31/366 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); C07D 311/80 (2013.01);
Abstract

Disclosed are methods, compounds, and compositions useful for increasing autophagy and promoting longevity. The methods, compounds, and compositions relate to urolithins and urolithin precursors and use thereof. Certain urolithins are represented by Formula I, while certain urolithin precursors are represented by Formula IV. The urolithin may be urolithin A, urolithin B, urolithin C, or urolithin D. The urolithin precursor may be ellagic acid or an ellagitannin. The methods include in vivo, ex vivo, and in vitro uses of the compounds and compositions.


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