The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2024
Filed:
Aug. 16, 2021
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Yaiza Diaz-De-Durana, San Diego, CA (US);
Michael DiDonato, San Diego, CA (US);
Christophe Filippi, Studio City, CA (US);
Shelly Meeusen, Rancho Santa Fe, CA (US);
Glen Spraggon, San Diego, CA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A23L 7/10 (2016.01); A23L 7/104 (2016.01); B02B 1/04 (2006.01); B02C 4/06 (2006.01); B02C 4/16 (2006.01); B02C 9/00 (2006.01); B02C 23/18 (2006.01); B02C 23/40 (2006.01); C07K 16/46 (2006.01); B02C 15/14 (2006.01);
U.S. Cl.
CPC ...
A23L 7/197 (2016.08); A23L 7/104 (2016.08); A61K 38/2013 (2013.01); B02B 1/04 (2013.01); B02C 4/06 (2013.01); B02C 4/16 (2013.01); B02C 9/00 (2013.01); B02C 23/18 (2013.01); B02C 23/40 (2013.01); C07K 16/46 (2013.01); A23V 2002/00 (2013.01); B02C 15/14 (2013.01);
Abstract
The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.