The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2024
Filed:
Jun. 17, 2021
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Diana Rose Ranoa, Champaign, IL (US);
Robin L. Holland, Urbana, IL (US);
Fadi G. Alnaji, Urbana, IL (US);
Kelsie J. Green, Champaign, IL (US);
Leyi Wang, Mahomet, IL (US);
Christopher B. Brooke, Champaign, IL (US);
Martin D. Burke, Champaign, IL (US);
Timothy M. Fan, Mahomet, IL (US);
Paul J. Hergenrother, Champaign, IL (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Abstract
A saliva-based testing method that bypasses the need for RNA isolation/purification is described herein. In experiments with inactivated SARS-CoV-2 virus spiked into saliva, this method has a limit of detection of 500-1000 viral particles per mL, rivalling the standard NP swab method. Initial studies showed excellent performance with 100 clinical samples. This saliva-based process is operationally simple, utilizes readily available materials, and can be easily implemented by existing testing sites thus allowing for high-throughput, rapid, and repeat testing of large populations.