The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2024
Filed:
May. 03, 2022
Nitto Denko Corporation, Osaka, JP;
Kenjirou Minomi, Osaka, JP;
Jens Harborth, San Diego, CA (US);
Cima Cina, San Diego, CA (US);
Wenbin Ying, San Diego, CA (US);
Jane Zheng, San Diego, CA (US);
Narendra Vaish, Kirkland, WA (US);
Nitto Denko Corporation, Osaka, JP;
Abstract
This invention provides compounds, compositions and methods for modulating the expression of target genes using RNA interference. RNAi structures and molecules of this invention can be used for modulating or silencing the expression of genes, with high levels of RNAi activity and reduced off target actions. Advantageous structures include siRNAs targeted to any gene having one or more 2′-deoxy nucleotides located in the seed region. The RNA interference molecules can be used in methods for preventing or treating diseases.