The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2024
Filed:
Mar. 23, 2020
Applicants:
Board of Regents, the University of Texas System, Austin, TX (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Inventors:
Raghu Kalluri, Houston, TX (US);
Sónia Melo, Oporto, PT;
Assignees:
Board of Regents, The University of Texas System, Austin, TX (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 39/00 (2006.01); C07K 14/47 (2006.01); C07K 16/40 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); G16B 20/00 (2019.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07K 14/4703 (2013.01); C07K 16/40 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57488 (2013.01); G16B 20/00 (2019.02); A61K 2039/505 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2333/4704 (2013.01); Y02A 90/10 (2018.01);
Abstract
Methods for diagnosis and treatment of cancers by use of exosomes comprising miRNAs and precursors thereof. For example, in some aspects, a cancer may be diagnosed or evaluated by determining the miRNA content of exosomes in a sample from a subject or by detecting miRNA processing in exosomes.