The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2024
Filed:
Aug. 31, 2018
Applicant:
Humabs Biomed SA, Bellinzona, CH;
Inventor:
Davide Corti, Bellinzona, CH;
Assignee:
HUMABS BIOMED SA, Bellinzona, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/00 (2006.01); A61P 31/14 (2006.01); C12N 15/85 (2006.01); G01N 33/569 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1081 (2013.01); A61P 31/14 (2018.01); C12N 15/85 (2013.01); G01N 33/56983 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 48/00 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); G01N 2333/185 (2013.01); G01N 2800/26 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention relates to multispecific antibodies, and antigen binding fragments thereof, that specifically bind to distinct Zika virus epitopes and potently neutralize infection of ZIKV. The invention also relates to nucleic acids that encode such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments of the invention in prophylaxis and treatment of ZIKV infection.