The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2024
Filed:
Jan. 27, 2023
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Alonso Jose Arguelles Delgado, Indianapolis, IN (US);
Boris Arnoldovich Czeskis, Carmel, IN (US);
Mai Khanh Nguyen Hawk, Indianapolis, IN (US);
Douglas Patton Kjell, West Lafayette, IN (US);
Yu Lu, Zionsville, IN (US);
Nicholas Andrew Magnus, Indianapolis, IN (US);
David Michael Remick, Fishers, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); B01J 23/44 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); B01J 23/44 (2013.01);
Abstract
Disclosed are methods of making selective estrogen receptor degraders (SERDs) of Formula A, as well as intermediates thereof, salts thereof including a pharmaceutically acceptable salt, and pharmaceutical compositions thereof: wherein either Ror Ris independently Cl, F, —CF, or —CH, and the other is H; and Ris H or PG.