The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2024

Filed:

Feb. 09, 2018
Applicant:

Eli Lilly and Company, Indianapolis, IN (US);

Inventors:

William Godwin Atterbury, Columbus, OH (US);

Corrie Jo Bennison, Lewis Center, OH (US);

Robert Jonathan Cain, Lewis Center, OH (US);

Michael Funk Chiappetta, Greenwood, IN (US);

Jeffrey Leclair Ellis, Columbus, OH (US);

David Arthur Holley, Lancaster, OH (US);

Mark Lafever, Indianapolis, IN (US);

Beverly Ann Piatt, Columbus, OH (US);

John Paul Tallarico, Powell, OH (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/20 (2006.01); A61M 5/31 (2006.01);
U.S. Cl.
CPC ...
A61M 5/2046 (2013.01); A61M 2005/2073 (2013.01); A61M 2005/3125 (2013.01); A61M 2205/0216 (2013.01); A61M 2205/7536 (2013.01);
Abstract

Processes and devices provide parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. A device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.


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