The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2024

Filed:

Sep. 19, 2017
Applicants:

David Weiner, Merion, PA (US);

Karuppiah Muthumani, Cherry Hill, NJ (US);

Jian Yan, Wallingford, PA (US);

Inventors:

David Weiner, Merion, PA (US);

Karuppiah Muthumani, Cherry Hill, NJ (US);

Jian Yan, Wallingford, PA (US);

Assignees:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA (US);

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 31/7088 (2006.01); A61K 39/42 (2006.01); A61P 31/14 (2006.01); C07K 14/18 (2006.01); C07K 16/10 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/42 (2013.01); A61K 31/7088 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); C07K 14/18 (2013.01); C07K 16/10 (2013.01); C07K 16/1081 (2013.01); C12N 7/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); C07K 2317/56 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24171 (2013.01); Y02A 50/30 (2018.01);
Abstract

Disclosed herein is a composition comprising a recombinant nucleic acid sequence that encodes an antibody to a Zika viral antigen, and functional fragments thereof. The invention also relates to a composition comprising the combination of a first composition that elicits an immune response in a mammal against zika virus and a second composition comprising a recombinant nucleic acid sequence encoding an antibody, a fragment thereof, a variant thereof, or a combination thereof. In some instances, the nucleic acid molecule comprises a nucleotide sequence encoding an anti-ZIKV-Envelope (anti-ZIKV E) Protein antibody.


Find Patent Forward Citations

Loading…