The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
Jun. 06, 2019
Oxford Nanopore Technologies Plc, Oxford, GB;
James Anthony Clarke, Oxford, GB;
James White, Oxford, GB;
Richard Muscat, Oxford, GB;
Jessica Mary May Johnson, Oxford, GB;
Ramiz Iqbal Nathani, Oxford, GB;
Andrew John Heron, Oxford, GB;
Mark John Bruce, Oxford, GB;
Lakmal Nishantha Jayasinghe, Oxford, GB;
Domenico Caprotti, Oxford, GB;
David Jackson Stoddart, Oxford, GB;
Rebecca Victoria Bowen, Oxford, GB;
Christopher James Wright, Oxford, GB;
Paul Richard Moody, Oxford, GB;
Oxford Nanopore Technologies PLC, Oxford, GB;
Abstract
Methods of characterizing an analyte using a detector such as a nanopore and an enzyme are provided. One aspect features methods for characterizing a double-stranded polynucleotide using a detector, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.