The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2024

Filed:

Jul. 09, 2019
Applicant:

Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory, Shaoxing, CN;

Inventors:

Xinde Xu, Shaoxing, CN;

Tian Xie, Shaoxing, CN;

Shengfan Wang, Shaoxing, CN;

Qiuyan Wang, Shaoxing, CN;

Jianyong Zheng, Shaoxing, CN;

Zhaowu Zeng, Shaoxing, CN;

Xiaopu Yin, Shaoxing, CN;

Xuejun Lao, Shaoxing, CN;

Kangzhong Shao, Shaoxing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 403/24 (2006.01); C12P 23/00 (2006.01);
U.S. Cl.
CPC ...
C12P 23/00 (2013.01); C07C 403/24 (2013.01); C07B 2200/13 (2013.01); C07C 2601/16 (2017.05);
Abstract

A method for extracting and isolating a lutein crystal from a vegetable oil resin containing a lutein diester, comprises: dissolving lipase into deionized water to form an enzyme solution; dissolving a lutein extract into an alcohol solvent containing the deionized water to form a uniform alcohol solution; adding the enzyme solution to the alcohol solution for performing hydrolysis, and stirring same to obtain a lutein solution; filtering and performing filtration isolation on the lutein solution to obtain a crystalline; re-dissolving the crystalline into a non-polar organic solvent, and using deionized water for washing a water-soluble impurity; recycling and cooling the organic solvent to obtain a recrystallization; and isolating and drying the recrystallization to obtain the lutein crystal. In this method, selectivity is strong, reaction time is short, no waste water is produced, process is environment-friendly and suitable for industrial production, and obtained lutein crystal is high in purity and yield.


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