The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2024
Filed:
Aug. 25, 2017
Applicant:
The Council of the Queensland Institute of Medical Research, Herston, AU;
Inventors:
Enzo Porrello, St. Lucia, AU;
James Hudson, St. Lucia, AU;
Drew Titmarsh, St. Lucia, AU;
Richard Mills, St. Lucia, AU;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12M 1/32 (2006.01); C12M 1/34 (2006.01); C12Q 1/02 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12M 23/12 (2013.01); C12M 41/00 (2013.01); C12Q 1/025 (2013.01); C12N 2500/16 (2013.01); C12N 2500/34 (2013.01); C12N 2500/36 (2013.01); C12N 2500/38 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/999 (2013.01); C12N 2503/02 (2013.01); C12N 2506/02 (2013.01); C12N 2513/00 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01);
Abstract
A cardiomyocyte maturation medium comprises a base medium, one or more fatty acids such as palmitic acid, glucose and albumin. The one or more fatty acids and glucose are ideally present at a concentration ratio of about 1:10. Typically, the medium does not comprise TGF or insulin, or comprises minimal TGF and/or insulin. A cell culture vessel is provided that comprises opposed poles that facilitate force measurements of developing cardiac muscle.