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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11920149 B1

PDFFull Text
Date of Patent:
Mar. 05, 2024

Filed:

Mar. 27, 2018

Diaphragm-specific nucleic acid regulatory elements and methods and use thereof

Applicant:

Vrije Universiteit Brussel, Brussels, BE;

Inventors:

Lay Khim Chuah, Bierbeek, BE;

Thierry Vandendriessche, Bierbeek, BE;

Warut Tulalamba, Brussels, BE;

Assignee:

VRIJE UNIVERSITEIT BRUSSEL, Brussels, BE;

Attorney:

Wenderoth, Lind & Ponack, L.L.P.

Primary Examiner:

Nicole Kinsey White

Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); A61P 21/00 (2006.01); C12N 9/24 (2006.01); C12N 9/26 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 48/00 (2013.01); A61P 21/00 (2018.01); C12N 9/2408 (2013.01); C12Y 302/0102 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/22 (2013.01); C12N 2830/008 (2013.01);
Abstract

The present invention relates to nucleic acid regulatory elements that are able to enhance diaphragm-specific expression of genes, in particular expression in diaphragm as such, or in combination with expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly diaphragm-directed gene therapy, and for vaccination purposes.

Find Patent Forward Citations

Chuah, Lay. (2024). Diaphragm-specific nucleic acid regulatory elements and methods and use thereof (U.S. Patent No. 11920149). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11920149

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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